List of Members of ISMMA , Statistical Inference

Research Group

Please, remove the '*' symbols from e-mail addresses to obtain the correct e-mail address

Name Function  E-mail Address
Alexandru AGAPIE   agapie*@* 
Bogdan ALEXE   balexe*@* 
Luiza BADIN   lbadin*@* 
Voicu Radu BOSCAIU   vboscaiu*@* 
Cornelia ENĂCHESCU Head of Department
Denis ENACHESCU   denachescu*@* 
Florentina SUTER   fsuter*@* 
Aida TOMA   atoma*@* 
Silviu VASILE   vslsilviu*@* 
Raluca VERNIC   rvernic*@* 


We are surmounted by data – scientific data, numerical data, demographic data, financial data and marketing data. Human attention has become a precious resource. So, we must find ways to automatically analyze the data, to automatically classify it, to automatically summarize it, to automatically discovers and characterize trends in it; briefly to find out automatically knowledge and new information. The aim of the researches carried out by the team is the “mining in data” using multivariate statistical linear and nonlinear models.

The basic aspects of the mathematical research consist in:

  • Evolutionary algorithms for function optimization and parameter fitting. Stochastic modeling and convergence rate analysis for particular classes of evolutionary algorithms working on finite/continuous search spaces;
  • Bootstrap and other resembling methods, nonparametric statistics and econometrics, statistical inference in production frontier models
  • Robust statistical inference. Applications of divergence criteria in statistical inference. Minimum distance methods.
  • Computer Vision Object detection/ Object recognition
  • Supervised and unsupervised statistical learning using neural networks and support vector machines;
  • Data analysis, biostatistics and biometrics, scientometrics;  
  • Functional, fractal nonlinear response with application to biochemical kinetics, allometry and population genetics;
  • Transition event statistics in genetics and disordered kinetics. Theoretical approaches for extracting rate distributions from experimental data;
  • Statistical approaches for microarray analysis;
  • Actuarial mathematics.

Algorithms, computer codes and numerical simulations naturally end the research carried on within this group.


Books, 2005-2010
  1. Alexandru Agapie, Evolutionary algorithms – modeling and convergence, 2007, ISBN 978-973-27-1509, Editura Academiei Române, 2007, 115 p.
  2. Gheorghe Cenusa, Bogdan Iftimie, Constantin Raischi, Iulian Mircea, Luiza Badin, Ovidiu Veghes, Marius Giuclea, Mihaela Covrig, Admitere 2009 Teste Grila si de autoevaluare, Editura Cison Bucuresti, 241 pg, 2009, ISBN 978-973-8301-18-4.
  3. Denis Enachescu, Data Mining. Metode si aplicatii, Editura Academiei Române, 373 pg., 2009,  ISBN 978-973-27-1798-1.
  4. Aida Toma, Metode robuste de estimare multidimensionala, Editura MatrixRom, 150 pg., 2009, ISBN 978-973-755-469-7.
  5. Bjorn Sundt, Raluca Vernic, Recursions for convolutions and compound distributions with insurance applications, EAA Lecture Notes, 345 pp., Springer 2009.
  6. Cornelia Enachescu, A. Constantinescu, Modele statistice in cazul masuratorilor repetate. Aplicatii in teledetectia datelor din agricultura, 2007, Ed. Bibliotheca (Ed. Acreditata CNCSIS cu avizul 1142/30 iunie 2003, reacreditata in mai 2006), ISBN 978-973-712-229-2, 126 p.
Chapters in books, 2005-2010
  1. Denis Enachescu, L.P. Dinu,Languages Similarity. Measuring and Testing,Recent Advances in Stochastic Modelling, Ed. Ch. H. Skiadas, ISBN 978-981- 270-968-4, World Scientific, 2007, 512-521.
  2. Denis Enachescu, L.P. Dinu, 2007, On clustering Romance Languages,Recent Advances in Stochastic Modelling, Ed. Ch. H. Skiadas, ISBN 978-981-270-968-4, World Scientific, 521-529.
  3. Voicu Boscaiu, Introducere in verificarea ipotezelor statistice pentru microarrays. In Bioinformatica Vol II, Editor Manuela Elisabeta Sidoroff, pag 12-19, Editura Tehnica, 2008
  4. C. Mircioiu, C. Enachescu, D.Enachescu,R.C. Sandulovici, Aplicatii Numerice de Statistica in Farmacie si in Studii Clinice, vol II, Metode Computerizate, Editura Universitara Carol Davila, Bucuresti, 2008, ISBN 978-973-708-222-0.
  5. Florentina Suter, F. Spizzichino, Generalized Marshall-Olkin Models: Ageing and Dependence Properties, in Advances in Mathematical Modelling for Reliability, Eds. Bedford, T., Quigley, J., Walls, L., Alkali, B., Daneshkhah, A. and Hardman, G., IOS Press, The Netherlands, 149-157, 2008
  6. Gheorghe Cenusa, Bogdan Iftimie, Constantin Raischi,, Iulian Mircea, Luiza Badin, Ovidiu Veghes, Marius Giuclea, Mihaela Covrig, Admitere 2009 Teste Grila si de autoevaluare, Editura Cison Bucuresti, 241 pg, 2009, ISBN 978-973-8301-18-4.
  7. Cornelia Enachescu, Denis Enachescu, Autoregressive systems with double-exponentially distributed noise, in “Systems Theory Modeling, Analysis and Control”, eds. A.El Jai, L.Afifi, E.Zerrik, Fes, Morocco, p.433-440, Presses Universitaires de Perpignan, ISBN 978-2-35412-043-6, 2009
  8. Denis Enachescu, Cornelia Enachescu, A new approach for outlying records in bioequivalence trials, in Selected papers of „The XIIIth International Conference-Applied Stochastic Models and Data Analysis”, eds. L. Sakalauskas, C.Skiadas, E.K.Zavadskas, Vilnius, Lithuania, p. 250-257, VGTU Press „Technika”, ISBN 978-9955-28-463-5, 2009
Articles, 2005-2010
  1. Marcel. O. Vlad, Stefan E. Szedlacsek, Nader Pourmand, L. Luca Cavalli-Sforza, Peter J.Oefner, John Ross, Fisher theorems for multivariable, time and space-dependent systems, with applications to population genetics and chemical kinetics. Proceedings of the National Academy of Science (PNAS, U.S.A.) 102, 9848-9853 (2005).F.I.= 9.643
  2. Marcel O. Vlad, Gianfranco Cerofolini, Peter J. Oefner, John Ross, Random rate processes with random energy barriers. Journal of Physical Chemistry, 109, pp. 21228-21234 (2005).F.I.=4.115
  3.  Marcel O. Vlad, John Ross, Exact solutions for the entropy production of severalIrreversible processes. Journal of Physical Chemistry, 189, pp. 10607-10612 (2005). F.I.=4.115
  4. Marcel O. Vlad, Arjang Hassibi, Christopher Contag, Maryam Hafezi, Thomas H. Lee,Ronald W. Davis & Nader Pourmand , Bioluminescence regenerative cycle (BRC) system:Theoretical considerations for nucleic acid quantification assays. Biophysical Chemistry116, pp. 175-185 (2005).F.I.=1.784
  5. Marcel O. Vlad, Vlad T. Popa, E. Segal, John Ross, Multiple rate-determining steps fornonideal and fractal kinetics. Journal of Physical Chemistry B, 109(6) pp. 2455–2460 (2005). F I=4.115
  6. Voicu Boscaiu , Guja Cornelia, Dumitrascu Anda, Baciu Adina, Debretin Mirela, PavelAlina, Choroid plexus – pineal gland correlations. Medical anthropology-computedtomography studies. Intracranial physiological calcification. Acta Endocrinologica,Romanian Academy, vol.I, January-March, 2005, pp. 1-19.
  7. Cornelia Enachescu, Statistical methods for establihing the risk factors in the involutional osteoporosis. Lecture Notes of the International Centre of Biocybernetics, World Health Organization collaborating Centre for Research and Training in Biocybernetics and Biomedical Engineering, Edited by Polish Academy of Science,Warsaw, Poland, (2005), pp. 19-24.
  8. Cornelia Enachescu, Denis Enachescu, Estimating an endpoint of a distribution in thepresence of observation errors using Support Vector Machines. Rev. RoumaineMath.Pures Appl., 50, 4, (2005) pp. 343-355.
  9. Voicu Boscaiu, Viorel Voda, Capabilitatea proceselor tehnologice(I). Calitatea, an 7,nr. 3 pp. 57-62 , 2006.
  10. Voicu Boscaiu, Viorel Voda, Capabilitatea proceselor tehnologice(II). Calitatea, an 7,nr. 4 pp. 57-60, 2006.
  11. Voicu Boscaiu, Viorel Voda, Capabilitatea proceselor tehnologice(III). Calitatea, an 7,nr. 5 pp. 55-59, 2006.
  12. Voicu Boscaiu, Viorel Voda, Isaic-Maniu, Marca de calitate sau brand?Calitate siManagement, an V, nr. 7 pp. 40-43, 2006.
  13. Cornelia Enachescu, Some practical problems of compartmental modelling. Math.Reports, 8(58) (2006) pp. 137-150.
  14. Cornelia Enachescu, Denis Enachescu, A multilayer perceptron network for the foetalweight prediction. Analele Univ. Buc., seria inf, XLV, (2006), pp. 73-84.
  15. Marcel. O. Vlad, Peter Oefner, John Ross, Transition Event Statistics in Genetics andDisordered Kinetics. Theoretical Approaches for Extracting Rate Distributions fromExperimental Data. Journal of Physical Chemistry B, 110, 18945-18952 (2006). F.I.=4.115
  16. Marcel O. Vlad, G.F. Cerofolini, D. Macolo, A model for oxidation kinetics in air at roomtemperature of hydrogen-terminated (100) Si. Journal of Applied Physics, 100, (11 pages)pp. 054308 (2006). F.I.=2.316
  17. Alexandru Agapie, Mircea Agapie , Transition functions for evolutionary algorithms oncontinuous state-space. J. Math. Model. Algorithms 6, No. 2, pp. 297-315 (2007).
  18.  Alexandru Agapie, R.. Höns, Analysis of a Voter model, Mathematical Reports, Ed.Acad. Romane, 9/59(2), 2007, pp.135-145.
  19. Alexandru Agapie, Mircea Agapie, On some theoretical properties of (1+1)evolutionary algorithms, Revue Roumaine de Mathematique Pures et Appliquees, 52(3), 2007, pp.287-303.
  20. Voicu Boscaiu, Bratosin D., Takacs L., Gheorghe A.-M., Sidoroff M., Tcacenko L.,Ponepal C., Buruiana V., Hermenean A., Ardelean A., Montreuil J., Marinescu Al. G.,Flow cytometric measurement of reactive oxygen species produced in aluminiummediated-apoptosis of Rana nucleated erythrocytes. Romanian Biological Sciences,2007, vol. 5, nr. 3-4, pp. 29-36.
  21. Voicu Boscaiu, Bratosin D., Dinischiotu A., Postolache C., Sidoroff M., Takacs L.,Tcacenco L., Hermenean A., Buruiana V., Ponepal C., Ardelean A., Marinescu, Al. G.,Biomonitorizarea poluarii apelor in Romania - o necesitate de viitor cu dubl?important?. Studia Universitatis Vasile Goldis Arad, Seria Stiintele Vietii, Vol. 17, nr. 1,pp. 13 – 20, 2007.
  22. Voicu Boscaiu, Sidoroff M, Paun A, Bratosin D, Takacs L, Utilizarea regresiei logisticemultinomiale in toxicologie. Romanian Biological Sciences, 2007, vol. 5 nr. 3-4, pp. 37-44.
  23. Voicu Boscaiu, Paun A, Rodriguez-Paton, Bratosin D, Sidoroff M, Butu M, Simulareaproceselor subcelulare printr-un (nou) mod discret. Romanian Biological Sciences,2007, vol. 5 nr. 3-4, pp. 9-12.
  24. Viorel Gh. Voda, V. Boscaiu, Al. Isaic-Maniu, Piata cartii si principalele ei caracteristici. MANAGEMENT SI MARKETING, Anul II, nr. 3, 2007, pp. 47 – 66.
  25. Voicu Boscaiu, I.M. Stancu-Minasian, Viorel Voda, Defining hierarchies for bibliometric entities. Proc Services and Software Architectures, Infrastructures and Engineering for enhancing EU Citizen’s Quality of Life, May 18, 2007, ISBN 978-973-0-04939-8, pp.163-170
  26. Cornelia Enachescu, A. Constantinescu, Using multilayer neural networks to estimatethe parameters of the nonlinear Baret model. Biocybernetics and BiomedicalEngineering, VOL 27, PART 3, (2007), pp. 95-111, Polish Scientific Publishers.
  27. Cornelia Enachescu, Evaluation of some statistical methods for referring Women forbone densitometry. Biocybernetics and Biomedical Engineering, VOL 27, PART 3,(2007), pp. 43-58, Polish Scientific Publishers.
  28. Cornelia Enachescu, Some statistical techniques for outliers detection in bioequivalencestudies. Proceedings of the 29th International Conference -MEDINF 2007, ISSN 1843-651X, "Lucian Blaga" University of Sibiu Editing House, (2007), pp. 264-276.
  29. Cornelia Enachescu, Denis Enachescu, Nonstandard techniques for smart clustering.Application to the recommender systems for libraries. Proceedings of the WorkshopServices and Software Architectures, Infrastructures and Engineering for enhancing EUCitizen’s Quality of Life, May, 2007, Romanian Academy Library, ISBN 978-973-0-04939-8, (2007), pp. 176-184.
  30. Cornelia Enachescu , Stéphane Milcent, Marianne Lorenzano, Denis Enachescu,Philippe Birembaut, Frédéric Staerman, La ploide cellulaire:facteur prédictif de cancerde prostate localement avancé. Progrès en Urologie (ISSN 1761-676X); 2007, vol. 17, 4,pp. 819-824.
  31. Marcel O. Vlad, Alexandru Dan Corlan, Vlad T. Popa, and John. Ross, On anti-portfolioeffects in science and technology with application to reaction kinetics, chemical synthesis,and molecular biology. Proceedings of the National Academy of Science (PNAS, USA),104, pp. 18398-18403 (2007).F.I.=9.643
  32. Marcel O. Vlad, Federico Moran, Vlad T. Popa, Stefan E. Szedlacsek and John. Ross,Functional, Fractal nonlinear response with application to rate processes with memory,allometry, and population genetics. Proceedings of the National Academy of Science(PNAS, USA), 104, pp. 4798-4803 (2007). F.I.=9.643
  33.  Marcel O. Vlad, Federico Moran, M. Bustos, J.C. Trivino, J. Ross, Species Connectivitiesand Reaction Mechanisms from Neutral Response Experiments. Journal of PhysicalChemistry A., 111, pp. 1844-1851 (2007).F.I.=4.115
  34. Marcel O. Vlad, John Ross, Inverse problems for reaction-diffusion systems withapplication to geographical population genetics. Advances in Chemical Physics, 135, pp.173-187 (2007).
  35. Voicu Boscaiu, Viorel Gh.Voda, Aplicatii ale seriilor de timp vectoriale in controlul calitatii(I), Calitate si Management, Nr.11, An7, (2008), 46-47.
  36. Voicu Boscaiu, Viorel Gh.Voda, Aplicatii ale seriilor de timp vectoriale in controlul calitatii(II), Calitate si Management,, Nr.12, An7, (2008), 42-45
  37. Aida Toma, Minimum Hellinger distance estimators for multivariate distributions from the Johnson system, Journal of Statistical Planning and Inference, 138, 3, pp. 803-816, 2008 (ISI journal, Impact Factor: 0.725)
  38. Aida Toma, Robust estimations and tests using divergences and duality techniques, Proceedings of 4th International Conference on Applied Statistics, special number of Romanian Statistical Review, 5 pg., 2008.
  39. Adina Baciu, A.T. Ispas, Voicu Boscaiu, Anda Dumitrascu, M. Ciuhuta, Aspecte ale calcificarii glandei pineale si plexurilor coroide din perspectiva antropologiei medicale, Revista Româna de Anatomie Functionala si Clinica Macro- si Microscopica si de Antropologie, Vol.VIII, Nr.3, pp. 33-42, 2009.
  40. G. Coldea, Voicu Boscaiu, Manuela Elisabeta Sidoroff, Changes in the structure of alpine plant communities from the Rodna Mountains between 2001 and 2008, (Gloria Europe Project), Romanian Biological Science, Vol. VII, Nr. 1-4, pp. 81-88, (2009).
  41. Luiza Badin, Leopold Simar, A bias-corrected nonparametric envelopment estimator of frontiers, Econometric Theory, vol. 25, pp 1289-1318, 2009, Cambridge University Press, doi:10.1017/S0266466609090513 [ISI, factor de impact 0.768].
  42. Luiza Badin, Nonparametric Efficiency Analysis: Recent Developments, Proceedings of the Sixth Congress of Romanian Mathematicians, Bucharest 2007, vol. 1, pp. 433–438, 2009, Editura Academiei Române
  43. Adriana Agapie, Luiza Badin, Confidence Intervals for the Guesstimation Algorithm: a Bootstrap Approach, Economic Computation and Economic Cybernetics Studies and Research, Vol. 43, no.3, pp 167-178, 2009, ISSN-0424-267X  (indexat ISI ).
  44. Denis Enachescu, Cornelia Enachescu, Clustering and Spatial Variation in Risk, Biocybernetics and Biomedical Engineering, 29(2),p. 19-30, 2009 [ISI, factor de impact 0,333].
  45. Aida Toma, Optimal robust M-estimators using divergences, Statistics and Probability Letters, 79, 1, pp.1-5, 2009. Elsevier, ISSN 0167-7152 [ISI, factor de impact 0.386].
  46. Aida Toma, Integral representation for powers of elements in locally m-convex algebras and applications, Rendiconti del Circolo Matematico di Palermo, 58, pp.29-40, 2009. Springer-Verlag, ISSN 0009-725X.
  47. Anchang, B; Sadeh, MJ; Jacob, J; Tresch, A; Vlad, Marcel Ovidiu; Oefner, PJ; Spang, R, Modeling the temporal interplay of molecular signaling and gene expression by using dynamicnested effects models, Proceedings of the National Academy of Sciences of the United States of America 106(16), p. 6447-6452, ISSN0027-8424, 2009 (revista cotata ISI).
  48. Marcel Ovidiu Vlad,; Corlan, AD; Moran, F; Spang, R; Oefner, P; Ross, J, Kinetic laws, phase-phase expansions, renormalization group, and INR calibration, Proceedings of the National Academy of Sciences of the United States of America 106(16), p. 6465-6470, ISSN0027-8424, 2009, (revista cotata ISI).
  49. Velcescu, L., Vasile, L., Relational operators in heterogeneous random databases, IEEE Proc. of the 11th  International Symposium on Symbolic and Numeric Algorithms for Scientific Computing Timisoara (SYNASC), România, 2009, IEEE Computer Society Press, 2009, pp. 407-413.
  50. Velcescu, L., Vasile, L., Distribution of result sets cardinalities in heterogeneous random databases, Proc. of the First International Conference on Modeling and Development of Intelligent Systems (MDIS), Sibiu, România, 2009, pp. 316-324
  51. Alexandru Agapie,   Simple form of the stationary distribution for 3d cellular automata in a special case, Physica A (Statistical Mechanics and its Applications), Elsevier 389(13), 2010, pp. 2495-2499 [ISI, Impact Factor 1,562].
  52. Alexandru Agapie,  R. Hons, Ad. Agapie, Limit behavior of the exponential Voter model, Mathematical Social Sciences, Elsevier, 59(3), 2010, pp. 271-281, [ISI, Impact Factor 0,426]
  53. Alexandru Agapie, Estimation of distribution algorithms on non-separable problems, International Journal of Computer Mathematics, Taylor & Francis 87 (3), 2010 , pp. 491-508, [ISI, Impact Factor 0,546].
  54. Luiza Badin, L. Daraio, C., Simar, L., Optimal Bandwidth Selection for Conditional Efficiency Measures: a Data-driven Approach, European Journal of Operational Research, vol. 201, nr. 2, pp 633-640, 2010 [ISI, Impact factor 2.093].
  55. Denis Enachescu, Exploratory Data Analysis Methods for Comparison of Drug Dissolution Profiles, Journal Biocybernetics and Biomedical Engineering, vol.30, 2010 [ISI]
  56. Aida Toma, Samuela Leoni-Aubin, Robust tests based on dual divergence estimators and saddlepoint approximations, Journal of Multivariate Analysis, 101, 5, 1143-1155. (ISI, Impact Factor 1.017)
  57. Aida Toma, Robust tests based on density power divergence estimators and saddlepoint approximations, Mathematical Reports, Vol 12 (62), No 4/2010, pp. 383-392 (ISI).
  58.  Asimit, E. Furman, R. Vernic, On a multivariate Pareto distribution, Insurance: Mathematics and Economics 46, 308-316, 2010, [ISI, Impact factor 0.960].
  59. Cornelia Enachescu, Denis Enachescu, Dalia Miron, Flavian Radulescu, Cluster analysis for testing “similarity” of drug dissolution profiles, Analele Universitatii Bucuresti, seia Informatica, Anul LVIII- 2009, 174-182.